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Funciones / Functions

download_data()
Download the large data objects of the package
create_heatmap()
Create a ComplexHeatmap with row annotation
get_heatmap_mat()
Generate a heatmap-ready matrix from a DESeq2 object
process_go()
Process GO Enrichment Result from a Single File
reduce_go_terms()
Batch Reduce and Visualize GO Terms Across Multiple Datasets

Datos de las participantes / Participant data

metadata_cleaned
Sample metadata: group, cell type and clinical information
volunteer_info
Clinical information per volunteer

Datos de expresión / Expression data

filtered_txi
Gene-level RNA-seq quantification (tximport)
biotype_summary
Gene biotypes
dds
DESeqDataSet checkpoint from the RNA-seq lesson
zscore_mat
Z-score matrix checkpoint from the RNA-seq lesson

Resultados de las lecciones / Lesson results

de_results
Differential expression results checkpoint (SLE vs Ctrl by cell type)
go_results
Functional enrichment results checkpoint (g:Profiler)
de_celltype_results
Differential expression results: dendritic cells vs monocytes
go_celltype_results
Functional enrichment checkpoint: dendritic cells vs monocytes (g:Profiler)
de_interaction_results
Differential expression results: between-group comparison of contrasts
go_interaction_results
Functional enrichment checkpoint: between-group comparison of contrasts (g:Profiler)

Listas de genes / Gene lists

sle_genes
Genes associated with systemic lupus erythematosus (SLE)
isg_genes
Interferon-stimulated genes (ISGs)
dc_genes
Genes associated with dendritic cell differentiation and function
moDC_genes
Genes described in the differentiation of monocytes into moDCs
tolDC_genes
Transcriptional signature of tolerogenic dendritic cells (tolDCs)

Funciones obsoletas / Deprecated functions

processGO() Reduce_GOTerm()
Deprecated functions in GeneExprLupusMx